Integrity of Sympathetic Cardiovascular Function among Kids

This chapter discusses the Integrity of sympathetic cardiovascular function in kids whose parents have a history of diabetes. Cardiovascular and respiratory systems undergo extensive changes during foetal through neonatal life and infancy until early childhood. Thus, respiratory and cardiovascular physiology is different in young children, especially in neonates and infants, from that of older children and adults. The study procedure was carried out on healthy volunteer medical students of age group 18 to 25 years. History taking, general examination and systemic examination were done before the procedure. And the findings were entered in the prestructured profrorma. All the participants were asked to take rest for 10 minutes in supine position then pulse rate and blood pressure was measured by using standard protocol. Three readings were taken and the average of the three was taken as the resting use rate and blood pressure. The cardiovascular tests to measure cardiovascular Sympathetic autonomic response were performed. In both the research and control groups, the distribution of ages and sexes was almost identical. The study group's mean resting pulse, mean SBP, and mean DBP were somewhat higher than those of the control group, but the differences were not statistically significant. Orthostasis and Mean QTc interval tests, which measure sympathetic activity, did not reveal a statistically significant difference between the study and control groups, however the prolonged handgrip test did reveal a statistically significant difference between the study and control groups. It is concluded that early subclinical sympathetic autonomic neuropathy may develop in children of type 2 diabetic parents without the presence of long term hyperglycemia.