SYNTHESIS OF SOME CONDENSED 2-(6-iodo-4-oxoquinazolin-3(4H)-yl)acetohydrazide

EL-HASHASH, MAHER A. and BAKEER, HADEER M. and EL-SHAMY, IBRAHIM E. and AZIZ, ABDALLA O. ABDEL (2015) SYNTHESIS OF SOME CONDENSED 2-(6-iodo-4-oxoquinazolin-3(4H)-yl)acetohydrazide. Journal of Applied Chemical Science International, 5 (4). pp. 227-236.

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Abstract

A highly efficient and versatile synthetic approach to the synthesis of some new condensed 2-(6-iodo-4-oxoquinazolin-3(4H)-yl)acetohydrazide viz. 1,2,4-triazolyl- 11, 1,3,4-oxadiazolyl- 8a,b, 9, 1,3,4-thiadiazolyl- 12, and pyrazolylquinazolinone derivatives 13-15 is presented. Moreover, acyclo C-nucleoside 17 were obtained via heterocyclization reaction of 2-(6-iodo-4-oxoquinazolin-3(4H)-yl)acetohydrazide (3) with D-glucono-1,5-lactone. Spectral (IR, 1H NMR, 13C NMR) data, and elemental analyses confirmed the structures of the newly synthesized compounds.

Item Type: Article
Subjects: Opene Prints > Chemical Science
Depositing User: Managing Editor
Date Deposited: 13 Jan 2024 04:21
Last Modified: 13 Jan 2024 04:21
URI: http://geographical.go2journals.com/id/eprint/3277

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