Effect of Sumac on DNA: An Advanced Study

For a long time, R. coriaria has been used as a spice by grinding the dried fruits with salt, and it has
also been widely used as a medicinal herb in traditional medicine for its athero protective effect and its
ability to treat eye diseases, wounds, bowel disorders, ring worms and skin disorders. In addition, R.
coriaria has recently shown to have hepatoprotective, anti-ischemic, antimicrobial as well as
hypoglycemic, anti-tumor and hyperlipidemic effects. Volatile substances, flavonoids, tannins and
xanthones have been reported from this plant. Due to its easy collection and the remarkable biological
activities, R. coriaria has been used both as food and medicine in some parts of the world especially
in Iran.
Tannin extracted from Sumac possesses potent antimigratory activity. Sumac yield tannin a
substance used in vegetable tanning. Effect of TANNIN (plant polyphenolic compound) on DNA
extract from spinach has been studied. Tannin is extracted by using acetone extraction where DNA is
extracted by ethanol precipitation. The effect of tannin on DNA was studied by using different
concentrations (10% to 30%) of tannin. The Optical density (O.D.) values of DNA decreased over
incubation time indicating reduction in density upon addition of tannin which may be protective by
repairing DNA or preventing DNA damage.