Synovial Fluid Analysis and Biopsy in Diagnosis of Joint Diseases

Worldwide, Arthritis is a communal clinical incidence of joints, and very predominant chronic disease in India. To evaluate to affect 1% of world’s adult population. Biopsies of Synovial fluid are being done as an adjuvant technique to assist in the diagnosis of arthritis. It offers a non-invasive method to diagnose any condition of the joint like traumatic, non-inflammatory/ inflammatory. Cytomorphological examination of Synovial fluids received in the Department of Pathology, Sree Balaji Medical College and Hospital, Chennai. To examine the gross, microscopic, biochemical and microbiologic variations in the synovial fluid in percutaneous synovial biopsy along with synovial fluid analysis was studied in 102 enrolled cases of arthritis. The liquefied was subjected to physical, biochemical and cytological analysis. To correlate synovial fluid cytology with biopsies whenever possible to increase the accuracy of diagnosis. Synovial fluid analysis plays an important role in categorizing various arthritis and thereby helps in arriving at a diagnosis early.