Ano Rectal Plasmablastic Lymphoma in HIV Positive Patient - A Case Report

Plasmablastic lymphoma (PBL) is an aggressive subtype of non-Hodgkin’s lymphoma (NHL), classified as a distinct entity by the WHO (2008) which frequently arises in the oral cavity of HIV infected patients [1]. It is usually associated with EBV infections, and MYC gene rearrangements [2]. PBL remains a diagnostic and a therapeutic challenge with high rate of relapse and death. There is no standard of care for this entity; current understanding & knowledge of PBL relies primarily on case reports and small case series.

We present a case of primary Ano rectal plasmablastic Lymphoma in a 24 years old male HIV positive patient from Ethiopia who presented with a 3 months history rectal bleeding & abdominal pain.