Ibraliu, Alban and Trendafilova, Antoaneta and Anđelković, Boban and Qazimi, Bujar and Gođevac, Dejan and Bebeci, Ela and Stefkov, Gjoshe and Zdunic, Gordana and Aneva, Ina and Pasho, Ina and Petreska-Stanoeva, Jasmina and Alipieva, Kalina and Savikin, Katarina and Evstatieva, Ljuba and Menkovic, Nebojsa and Stefova, Marina and Popova, Milena and Jadranin, Milka and Todorova, Milka and Denev, Petko and Kulevanova, Svetlana and Bankova, Vassya and Gurazi, Vilma and Papajani-Toska, Vilma (2015) Comparative Study of Balkan Sideritis Species from Albania, Bulgaria and Macedonia. European Journal of Medicinal Plants, 5 (4). pp. 328-340. ISSN 22310894
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Abstract
Background: Sideritis scardica and S. raeseri are very popular medicinal plants in Albania, Macedonia, and Bulgaria.
Objective: Comparison of the phenolic, flavonoid, and diterpene contents and detailed chemical profiles, as well as data on antioxidant activity, comprising plant material from different locations in the Balkan Peninsula.
Materials and Methods: Total phenolic and flavonoid contents for the studied Sideritis samples were determined spectrophotometrically. By HPLC-DAD-ESI-MSn analysis, 48 individual phenolic constituents were completely or tentatively identified. Chemical profiling of Sideritis major diterpenes and their quantification was performed by HPLC-ESI-MSD TOF analysis. A combination of two methods (ORAC and DPPH) was applied for evaluation of the antioxidant capacity of Sideritis extracts.
Results: The results obtained demonstrated that Sideritis samples (S. scardica and S. raeseri) collected from Albania, Bulgaria and Macedonia are similar in their chemical profiles (they all contain phenylethanoid glycosides, flavonoid 7-O-diglycosides and acetylated flavonoid 7-O-diglycosides, and diterpenes: main components siderol and sideridiol); and antioxidant activity. Although some differences exist, they are not essential.
Conclusion: This fact is a good basis for the formulation of range for parameters for quality control of Sideritis extracts and plant material. The studied cultivated plant material is similar in its chemical composition, profile and antioxidant activity to the wild growing samples.
Item Type: | Article |
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Subjects: | Opene Prints > Medical Science |
Depositing User: | Managing Editor |
Date Deposited: | 03 Jun 2023 04:20 |
Last Modified: | 17 Jan 2024 04:13 |
URI: | http://geographical.go2journals.com/id/eprint/2069 |